Human sexuality manifests itself in the unfolding of an opposition between universal procreation and individual enjoyment. In this opposition the author detects the knotting of two drives in an apparent juxtaposition: Eros and death drive. On the basis of the three tragedies of the Theban cycle of Sophocles, he investigates how the (un)knotting of this drive culminates in a (death)desire in its purest form. The themes that follow (subjective death wish, blinding ignorance, unconscious transgression of the Law, lethal enjoyment, impossible femininity, impotent masculinity, unbreakable blood ties,…) are linked to the management of this desire within the ethics of contemporary psychoanalysis, more specifically with regards to the end of the cure. From the impasse that comes with this end, the author traces the shift in answers to the questions regarding the end of analysis in the work of Jacques Lacan, from subjective death in the cure, through the traversing of the phantasm, to the last approach to the passe and the creation of the sinthome. In these times of the pluralisation of the Names-of-the-Father he demonstrates how the tragedy in Greek Antiquity still delivers us a solid mythical foothold, now that the object a is climbing into the zenith.