This article broadly discusses the concept of the death drive. It demonstrates how a biological frame of reference is inadequate for interpreting the (sexual) drive. The notion of the compulsion to repeat helps us to understand why Freud was forced to introduce the death drive and, at the same time, to acknowledge it as being the underlying determining principle of every drive. Making use of the notions das Ding and objet a we show how Lacan’s reading of this controversial concept of the death drive precludes an organic interpretation. Finally, two clinical fragments illustrate how the activity of the death drive may reveal itself.